TheantibodyisdirectedagainstthePuumala
SEROtypenucleocapsidproteinwhichhasbeenshowntobethemajorimmunogenininfections(HFRS,Nephropathiaepidemica)causedbyPuumalaVirus.
Positivecross-reactionwithSinNombreVirus(SNV).
Nocoss-reactionwithHantaan-relatedserogroups,likeDobrava,Seoul.